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. 1974 Sep;10(3):624–632. doi: 10.1128/iai.10.3.624-632.1974

Serological Comparison of Five Arginine-Utilizing Mycoplasma Species by Two-Dimensional Immunoelectrophoresis

Charles E Thirkill 1, George E Kenny 1
PMCID: PMC422997  PMID: 4473427

Abstract

Five arginine-utilizing, nonglycolytic Mycoplasma species were compared serologically by two dimensional immunoelectrophoresis. The survey included: Mycoplasma hominis, Mycoplasma arthritidis, Mycoplasma gateae, Mycoplasma gallinarum, and three strains of Mycoplasma arginini. Although the M. arginini strains showed strong cross-reactions, each strain produced a different antigenic profile which was distinct and which indicated significant antigenic differences between strains. The M. arginini strains showed strong relationships with M. gateae; lesser cross-reactions were observed with other strains. Common antigens were demonstrable in the entire group. When all these species were compared with a glycolytic species, Mycoplasma gallisepticum, no cross-reactions were observed. Two-dimensional immunoelectrophoresis was a far more sensitive technique than double-immunodiffusion since as many as 20 components could be resolved.

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Selected References

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