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. 1975 Jun;72(6):2325–2329. doi: 10.1073/pnas.72.6.2325

Ribosomal protein S1 and polypeptide chain initiation in bacteria.

W Szer, J M Hermoso, S Leffler
PMCID: PMC432750  PMID: 1094462

Abstract

Among several subspecies of 30S subunits of Escherichia coli observed by polyacrylamide-agarose gel electrophoresis, only the slow-moving, protein S1-containing subspecies participates in the formation of the 30S initiation complex with coliphage MS2 RNA as mRNA; the other subspecies retain activity with AUG as mRNA; they are also active in the poly(U)-directed binding of Phe-tRNA. Protein S1 from Caulobacter crescentus substitutes for E. coli S1 despite the fact that C. crescentus ribosomes do not bind MS2 RNA. Under appropriate conditions, the entire population of E. coli 30S subunits can be isolated as the S1-containing subspecies. Protein S1 is lost by salt treatment of ribosomes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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