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. 1973 Jan;70(1):270–274. doi: 10.1073/pnas.70.1.270

Development of Acetylcholine Receptor Clusters on Cultured Muscle Cells

A J Sytkowski 1, Z Vogel 1, M W Nirenberg 1
PMCID: PMC433229  PMID: 4509661

Abstract

Clusters of acetylcholine receptors were formed in the absence of neurons during the development of cultured chick-embryo skeletal muscle cells. The average concentration of receptors in clusters was estimated to be 9000 per μm2. At other regions of the cell, receptor concentration was 900 per μm2. The possibility that receptor clusters may participate in synapse formation is suggested.

Keywords: α-bungarotoxin, autoradiography, synapses

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Selected References

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