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. 1973 Mar;70(3):747–749. doi: 10.1073/pnas.70.3.747

Protective Effect of Ascorbic Acid on Hepatotoxicity Caused by Sodium Nitrite Plus Aminopyrine

Jerome J Kamm 1, Theodore Dashman 1, A H Conney 1, J J Burns 1
PMCID: PMC433349  PMID: 4514987

Abstract

The oral treatment of rats with sodium ascorbate in combination with sodium nitrite and aminopyrine prevents the rise in serum alanine aminotransferase (EC 2.6.1.2) observed when nitrite and aminopyrine are given alone. Ascorbic acid also affords protection, whereas dehydroascorbic acid exerts no protective effect.

Keywords: rats, serum alanine aminotransferase

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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