Skip to main content
PMC home page
Thorax logoLink to Thorax
. 1976 Oct;31(5):507–516. doi: 10.1136/thx.31.5.507

Second primary lung carcinoma.

R A Smith, B K Nigam, J M Thompson
PMCID: PMC470467  PMID: 996813

Abstract

Ffity-five patients suffering from second primary lung carcinoma, 10 synchronous and 45 after resection for lung carcinoma (metachronous), have been observed from 1400 resections. The first manifestation of a second carcinoma in this series has always been the appearance of a new shadow in the follow-up radiograph. In our experience, second primary lung carcinoma is a disease affecting only heavy cigarette smokers. Heavy cigarette smokers suffering from squamous-cell carcinoma are at special risk. The results of re-operation, the significance of the time interval between the original operation and the appearance of the second primary carcinoma, and the slow growth rate of some second primaries are briefly discussed. No clear-cut methods exist for distinguishing a second primary from a metastasis from the original carcinoma.

Full text

PDF
510

Images in this article

513Image
on p.513
514Image
on p.514
515Image
on p.515

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AUERBACH O., STOUT A. P., HAMMOND E. C., GARFINKEL L. Changes in bronchial epithelium in relation to cigarette smoking and in relation to lung cancer. N Engl J Med. 1961 Aug 10;265:253–267. doi: 10.1056/NEJM196108102650601. [DOI] [PubMed] [Google Scholar]
  2. BELCHER J. R., ANDERSON R. SURGICAL TREATMENT OF CARCINOMA OF THE BRONCHUS. Br Med J. 1965 Apr 10;1(5440):948–954. doi: 10.1136/bmj.1.5440.948. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BROCK R. THORACIC SURGERY: AND THE LONG-TERM RESULTS OF OPERATION FOR BRONCHIAL CARCINOMA. Ann R Coll Surg Engl. 1964 Oct;35:195–213. [PMC free article] [PubMed] [Google Scholar]
  4. Chaudhuri M. R. Independent bilateral primary bronchial carcinomas. Thorax. 1971 Jul;26(4):476–480. doi: 10.1136/thx.26.4.476. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. GLENNIE J. S., HARVEY P. W., SALAMA V. MULTIPLE PRIMARY CARCINOMA OF THE BRONCHUS. A REPORT OF THREE CASES. J Thorac Cardiovasc Surg. 1964 Jul;48:40–48. [PubMed] [Google Scholar]
  6. HUGHES R. K., BLADES B. Multiple primary bronchogenic carcinoma. J Thorac Cardiovasc Surg. 1961 Apr;41:421–429. [PubMed] [Google Scholar]
  7. LE GAL Y., BAUER W. C. Second primary bronchogenic carcinoma. A complication of successful lung cancer surgery. J Thorac Cardiovasc Surg. 1961 Jan;41:114–124. [PubMed] [Google Scholar]
  8. Neptune W. B., Woods F. M., Overholt R. H. Reoperation for bronchogenic carcinoma. J Thorac Cardiovasc Surg. 1966 Sep;52(3):342–350. [PubMed] [Google Scholar]
  9. ROBINSON C. L., JACKSON C. A. Multiple primary cancer of the lung. J Thorac Surg. 1958 Aug;36(2):166–173. [PubMed] [Google Scholar]
  10. Razzuk M. A., Pockey M., Urschel H. C., Jr, Paulson D. L. Dual primary bronchogenic carcinoma. Ann Thorac Surg. 1974 May;17(5):425–433. doi: 10.1016/s0003-4975(10)65675-5. [DOI] [PubMed] [Google Scholar]
  11. Shields T. W., Robinette C. D. Long term survivors after resection of bronchial carcinoma. Surg Gynecol Obstet. 1973 May;136(5):759–762. [PubMed] [Google Scholar]
  12. Struve-Christensen E. Diagnosis and treatment of bilateral primary bronchogenic carcinoma. J Thorac Cardiovasc Surg. 1971 Apr;61(4):501–513. [PubMed] [Google Scholar]
  13. WATSON W. L. TEN-YEAR SURVIVAL IN LUNG CANCER. A STUDY OF 56 CASES. Cancer. 1965 Feb;18:133–135. doi: 10.1002/1097-0142(196502)18:2<133::aid-cncr2820180202>3.0.co;2-n. [DOI] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES