Abstract
A 52 year old man who had been receiving haemodialysis for 13 years, with a history of renal tuberculosis, right ischial tuberculous osteomyelitis, and dialysis arthropathy, developed a soft tissue tumour in his left buttock. Histological analysis, immunohistological staining, and electron microscopic examination of the surgically removed tumour showed massive deposits of beta 2-microglobulin (beta 2-M) amyloid. This case shows the expanding clinical spectrum of this type of amyloidosis, and it is suggested that amyloid infiltration should be considered in the differential diagnosis of gluteal tumours in these patients.
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- Athanasou N. A., Chaplin A. J., Oliver D. O. Subcutaneous deposition of beta 2-microglobulin amyloid in a long-term haemodialysis patient. Nephrol Dial Transplant. 1990;5(10):878–881. doi: 10.1093/ndt/5.10.878. [DOI] [PubMed] [Google Scholar]
- Brancaccio D., Gallieni M., Padovese P., Anelli A., Coggi G., Uslenghi C. Dialysis amyloidosis with massive popliteal deposition of beta 2-microglobulin amyloid. Lancet. 1988 Oct 1;2(8614):802–802. doi: 10.1016/s0140-6736(88)92459-2. [DOI] [PubMed] [Google Scholar]
- Campistol J. M., Cases A., Torras A., Soler M., Muñoz-Gómez J., Montoliu J., López-Pedret J., Revert L. Visceral involvement of dialysis amyloidosis. Am J Nephrol. 1987;7(5):390–393. doi: 10.1159/000167505. [DOI] [PubMed] [Google Scholar]
- Casey T. T., Stone W. J., DiRaimondo C. R., Brantley B. D., DiRaimondo C. V., Gorevic P. D., Page D. L. Tumoral amyloidosis of bone of beta 2-microglobulin origin in association with long-term hemodialysis: a new type of amyloid disease. Hum Pathol. 1986 Jul;17(7):731–738. doi: 10.1016/s0046-8177(86)80183-6. [DOI] [PubMed] [Google Scholar]
- Floege J., Brandis A., Nonnast-Daniel B., Westhoff-Bleck M., Tiedow G., Linke R. P., Koch K. M. Subcutaneous amyloid-tumor of beta-2-microglobulin origin in a long-term hemodialysis patient. Nephron. 1989;53(1):73–75. doi: 10.1159/000185706. [DOI] [PubMed] [Google Scholar]
- Lusenti T., Borgatti P. P., Lindner G., Anelli A., Brancaccio D. Multiple tendineal tumoral amyloid masses in a patient on long-term dialysis. Nephron. 1991;57(2):243–244. doi: 10.1159/000186263. [DOI] [PubMed] [Google Scholar]
- Noël L. H., Zingraff J., Bardin T., Atienza C., Kuntz D., Drüeke T. Tissue distribution of dialysis amyloidosis. Clin Nephrol. 1987 Apr;27(4):175–178. [PubMed] [Google Scholar]
- Ogawa H., Saito A., Hirabayashi N., Hara K. Amyloid deposition in systemic organs in long-term hemodialysis patients. Clin Nephrol. 1987 Oct;28(4):199–204. [PubMed] [Google Scholar]
- Sethi D., Hutchison A. J., Cary N. R., Brown E. A., Curtis J. R., Woodrow D. F., Gower P. E. Macroglossia and amyloidoma of the buttock: evidence of systemic involvement in dialysis amyloid. Nephron. 1990;55(3):312–315. doi: 10.1159/000185981. [DOI] [PubMed] [Google Scholar]
- Theaker J. M., Raine A. E., Rainey A. J., Heryet A., Clark A., Oliver D. O. Systemic amyloidosis of beta 2-microglobulin type: a complication of long-term haemodialysis. J Clin Pathol. 1987 Oct;40(10):1247–1251. doi: 10.1136/jcp.40.10.1247. [DOI] [PMC free article] [PubMed] [Google Scholar]