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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2021 May 16:ciab446. doi: 10.1093/cid/ciab446

BNT162b2 mRNA vaccination did not prevent an outbreak of SARS COV-2 variant 501Y.V2 in an elderly nursing home but reduced transmission and disease severity

Benoit Bailly 1,2,, Luc Guilpain 3, Kevin Bouiller 2,4, Catherine Chirouze 2,4, Melissa N’Debi 5, Alexandre Soulier 6, Vanessa Demontant 5, Jean-Michel Pawlotsky 6,7, Christophe Rodriguez 5,6,7, Slim Fourati 6,7,
PMCID: PMC8241482  PMID: 33993228

Abstract

We report an outbreak of SARS-CoV-2 501Y.V2 in a nursing home. All non-vaccinated residents (5/5) versus half of those vaccinated with BNT162b2 (13/26) were infected. Two of 13 vaccinated versus 4 of 5 non-vaccinated residents presented severe disease. BNT162b2 did not prevent the outbreak, but reduced transmission and disease severity.

Keywords: SARS CoV-2, outbreak, variant, BNT162b2 vaccine, nursing home

Supplementary Material

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Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

ciab446_suppl_Supplementary_Figure_S1
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ciab446_suppl_Supplementary_Materials

Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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