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. 1990 Sep;10(9):4957–4960. doi: 10.1128/mcb.10.9.4957

Highly repeated sites in the apolipoprotein(a) gene recognized by methylated DNA-binding protein, a sequence-specific DNA-binding protein.

K C Ehrlich 1, M Ehrlich 1
PMCID: PMC361120  PMID: 2388631

Abstract

Methylated DNA-binding protein (MDBP), a sequence-specific DNA-binding protein, was found to recognize more than 30 sites within an allele of the human apolipoprotein(a) gene. High plasma levels of apolipoprotein(a), a risk factor for atherosclerosis, have been correlated with genetically inherited lower-molecular-mass isoforms of this protein. MDBP might help down modulate the expression of the apolipoprotein(a) gene in a manner dependent on the length of a given allele of the gene and the number of MDBP sites in it.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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