β-Actin-binding Complementarity-determining Region 2 of Variable Heavy Chain from Monoclonal Antibody C7 Induces Apoptosis in Several Human Tumor Cells and Is Protective against Metastatic Melanoma

Supplemental Data

Files in this Data Supplement:

• supplemental figure 1 (.pdf, 245 KB) - Disintegration of nuclear lamin following treatment with C7H2 peptide.
• supplemental figure 2 (.pdf, 295 KB) - C7H2 peptide induces DNA degradation in tumor cells.
• supplemental figure 3 (.pdf, 163 KB) - Caspase 8 activation and superoxide production induced by C7H2 peptide.
• supplemental figure 4 (.pdf, 2.2 MB) - TUNEL assay in C7H2-treated tumor cells.
• supplemental figure 5 (.pdf, 89 KB) - Binding of C4A peptide to b-actin and actin polymerization.
• supplemental figure 6 (.pdf, 597 KB) - Surface expression of β-actin in murine melanoma cells. Reactivity with anti-actin antibody and C7H2.